There is no gender difference (American Academy of Sleep Medicine ). 6,92–94 The prevalence of jet lag disorder (JLD) is not well established.
6,14,89–91 A few days after the travel, in the new time zone, the travelers complain of difficulty to fall asleep at night, difficulty to maintain alertness during day, fatigue and accompanying cognitive, physical, and behavioral symptoms like decrease in executive functions, decline in mood, changes in appetite, and constipation. Jet lag is a transient but repeatable disorder that comes to existence due to air travel crossing at least two time zones rapidly while the endogenous circadian rhythm cannot accommodate itself. Melatonin (as little as 0.5 mg 30 minutes prior to targeted bedtime) may be useful for reducing the severity of jet lag, A4 and zolpidem (5 mg) taken for a few nights at bedtime at the destination is generally effective.įüsun Mayda Domaç, in Neurological Modulation of Sleep, 2020 Jet Lag Disorder Jet lag ( Chapter 377) occurs after crossing three or more time zones. Aspirin therapy is of no proven benefit in this setting. Of many recommendations for prevention, only the use of graded 15 to 30 mm Hg compression stockings for those at higher risk is supported in trials, A3 although prophylactic antithrombosis agents such as factor Xa inhibitor, direct thrombin inhibitor, and subcutaneous low-molecular-weight heparin are sometimes used in practice. All travelers should avoid dehydration, avoid alcohol, and exercise the legs regularly in flight. Those with clear, known risk factors are at highest risk. Risk of pulmonary embolus is essentially absent on flights lasting less than 6 hours.
Travel-related immobility is associated with deep venous thrombosis and pulmonary embolism in otherwise healthy travelers. Lee Goldman MD, in Goldman-Cecil Medicine, 2020 Traveler’s Thrombosis and Jet Lag
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